金黄色葡萄球菌中一种35 kDa膜蛋白与渗透溶质转运之间的潜在联系。

Possible link between a 35 kDa membrane protein and osmolyte transport in Staphylococcus aureus.

作者信息

Pourkomaillan B

机构信息

Colworth Laboratory, Microbiology Department, Sharnbrook, Bedford, UK.

出版信息

Lett Appl Microbiol. 1998 Feb;26(2):149-52. doi: 10.1046/j.1472-765x.1998.00306.x.

DOI:10.1046/j.1472-765x.1998.00306.x

PMID:9569700

Abstract

Accumulation of proline and glycine betaine occurs via three transport systems in Staphylococcus aureus (Pourkomailian and Booth 1992, 1994). A 35 kDa membrane protein was identified to be missing from a mutant, BP108, which lacks activity of the low affinity osmolyte transport system. The loss in activity of the low affinity transport system may be linked to the loss in expression of the 35 kDa membrane protein as a result of transposon insertion.

摘要

在金黄色葡萄球菌中，脯氨酸和甘氨酸甜菜碱的积累通过三种转运系统实现（Pourkomailian和Booth，1992年，1994年）。已鉴定出一种35 kDa的膜蛋白在突变体BP108中缺失，该突变体缺乏低亲和力渗透溶质转运系统的活性。低亲和力转运系统活性的丧失可能与转座子插入导致的35 kDa膜蛋白表达缺失有关。