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本文引用的文献

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Accelerated development of genital Chlamydia trachomatis serovar E in McCoy cells grown on microcarrier beads.在微载体珠上生长的 McCoy 细胞中沙眼衣原体血清型 E 的加速发育。
Microb Pathog. 1996 Jan;20(1):31-40. doi: 10.1006/mpat.1996.0003.
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Cytotoxic-T-lymphocyte-mediated cytolysis of L cells persistently infected with Chlamydia spp.细胞毒性T淋巴细胞介导的对持续感染衣原体属的L细胞的细胞溶解作用
Infect Immun. 1996 Jun;64(6):1944-9. doi: 10.1128/iai.64.6.1944-1949.1996.
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IFN-gamma-mediated antimicrobial response. Indoleamine 2,3-dioxygenase-deficient mutant host cells no longer inhibit intracellular Chlamydia spp. or Toxoplasma growth.γ-干扰素介导的抗菌反应。吲哚胺2,3-双加氧酶缺陷型突变宿主细胞不再抑制细胞内衣原体属或弓形虫的生长。
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Morphologic and antigenic characterization of interferon gamma-mediated persistent Chlamydia trachomatis infection in vitro.体外干扰素γ介导的沙眼衣原体持续感染的形态学和抗原特性
Proc Natl Acad Sci U S A. 1993 May 1;90(9):3998-4002. doi: 10.1073/pnas.90.9.3998.
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Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence.色氨酸耗竭作为γ干扰素介导的衣原体持续存在的一种机制。
Infect Immun. 1994 Sep;62(9):3705-11. doi: 10.1128/iai.62.9.3705-3711.1994.
6
Immunoelectron-microscopic quantitation of differential levels of chlamydial proteins in a cell culture model of persistent Chlamydia trachomatis infection.沙眼衣原体持续感染细胞培养模型中衣原体蛋白差异水平的免疫电镜定量分析
Infect Immun. 1994 Sep;62(9):4059-62. doi: 10.1128/iai.62.9.4059-4062.1994.
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Reactivation of persistent Chlamydia trachomatis infection in cell culture.细胞培养中持续性沙眼衣原体感染的再激活
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Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis.沙眼衣原体主要外膜蛋白的纯化及部分特性分析
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Cell surface polarity in epithelia.上皮细胞的细胞表面极性
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Chlamydia trachomatis: its role in tubal infertility.沙眼衣原体：其在输卵管性不孕中的作用。
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γ干扰素对培养的极化和非极化人上皮细胞中沙眼衣原体生长的不同影响。

Differential effects of gamma interferon on Chlamydia trachomatis growth in polarized and nonpolarized human epithelial cells in culture.

作者信息

Kane C D, Byrne G I

机构信息

Department of Medical Microbiology and Immunology, University of Wisconsin, Madison 53706, USA.

出版信息

Infect Immun. 1998 May;66(5):2349-51. doi: 10.1128/IAI.66.5.2349-2351.1998.

DOI:10.1128/IAI.66.5.2349-2351.1998
PMID:9573129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC108203/
Abstract

The effects of gamma interferon (IFN-gamma) on Chlamydia trachomatis growth in polarized epithelial cells were examined. The range of IFN-gamma concentrations causing aberrant chlamydial growth was wider in polarized than in nonpolarized cultures. Results indicate that chlamydial growth modulation in polarized cells readily leads to persistence and better reflects in vivo conditions.

摘要

研究了γ干扰素（IFN-γ）对极化上皮细胞中沙眼衣原体生长的影响。导致衣原体异常生长的IFN-γ浓度范围在极化培养物中比在非极化培养物中更宽。结果表明，极化细胞中的衣原体生长调节容易导致持续性感染，并且能更好地反映体内情况。