Blaas H G, Eik-Nes S H
National Center for Fetal Medicine, Department of Obstetrics and Gynecology, University Hospital of Trondheim, Trondheim, N-7006, Norway.
Croat Med J. 1998 Jun;39(2):128-31.
Description of the development of the human embryonic brain visualized by transvaginal ultrasound. Methods. In two studies, healthy pregnant women without any pregnancy complications and normal outcomes were examined by transvaginal ultrasound in the early pregnancy between seven and twelve weeks of gestation. The hypoechogenic brain cavities were described and measured.
Initially, the rhombencephalic cavity was the largest brain cavity. It did not increase its size significantly during the first trimester. The mesencephalic cavity was rather large throughout the first trimester. The dimension of the future third ventricle decreased gradually. The hemispheres were the smallest cavities at the beginning of week seven. They grew fast and dominated the appearance of the embryonic brain from the week nine onwards.
Size and shape of the brain structures showed fast changes during the observation period. The ultrasound description of the brain development corresponded to that of classical embryology.
描述经阴道超声观察到的人类胚胎大脑发育情况。方法：在两项研究中，对无任何妊娠并发症且结局正常的健康孕妇，于妊娠7至12周的早孕期间进行经阴道超声检查。对低回声脑腔进行描述和测量。
最初，菱脑腔是最大的脑腔。在孕早期其大小无显著增加。中脑腔在整个孕早期都相当大。未来第三脑室的尺寸逐渐减小。在第7周开始时，半球是最小的腔。它们生长迅速，从第9周起主导胚胎大脑的外观。
在观察期内脑结构的大小和形状变化迅速。大脑发育的超声描述与经典胚胎学的描述相符。
