新型2-氨基-4-羟基-δ-戊内酰胺衍生物的合成及其对巴西日圆线虫的体外驱虫活性
Synthesis and in vitro anthelmintic activity against Nippostrongylus brasiliensis of new 2-amino-4-hydroxy-delta-valerolactam derivatives.
作者信息
Gordon S, Costa L, Incerti M, Manta E, Saldaña J, Domínguez L, Mariezcurrena R, Suescun L
机构信息
Cátedra de Química Farmacéutica, Fac. de Química, Universidad de la República, Montevideo, Uruguay.
出版信息
Farmaco. 1997 Oct;52(10):603-8.
PMID:9580122
Abstract
The synthesis of a series of 2-amino-4-hydroxy-delta-valerolactam derivatives is described (compounds 4 to 10). These compounds showed a high anthelmintic in vitro activity against the Nippostrongylus brasiliensis model.
摘要
本文描述了一系列2-氨基-4-羟基-δ-戊内酰胺衍生物（化合物4至10）的合成。这些化合物对巴西日圆线虫模型显示出高体外驱虫活性。
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