Davyt D, Entz W, Fernandez R, Mariezcurrena R, Mombrú A W, Saldaña J, Domínguez L, Coll J, Manta E
Facultad de Química, Universidad de la República, Av. Gral. Flores, 2124 Montevideo, Uruguay.
J Nat Prod. 1998 Dec;61(12):1560-3. doi: 10.1021/np980114c.
Chondriamide C (3), a new bis(indole) amide, was isolated from the red alga Chondria atropurpurea, and its structure was established from spectroscopic data and chemical transformations. A new natural product, 3-indoleacrylamide (4), and the previously described chondriamides A and B (1, 2) and 3-indoleacrylic acid (5) were also isolated. The anthelmintic activities of compounds 1, 3, 4, and 6 (the O,N1,N1'-trimethyl derivative of compound 2) against Nippostrongylus brasiliensis in vitro were evaluated.
