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在波多黎各经营射击馆的注射吸毒者中的风险行为、HIV血清阳性率及结核感染情况

Risk behaviors, HIV seropositivity, and tuberculosis infection in injecting drug users who operate shooting galleries in Puerto Rico.

作者信息

Robles R R, Marrero C A, Reyes J C, Colón H M, Matos T D, Finlinson H A, Muñoz A, Meléndez M, Sahai H

机构信息

Research Institute, Mental Health and Anti-Addiction Services Administration, San Juan, Puerto Rico, USA.

出版信息

J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Apr 15;17(5):477-83. doi: 10.1097/00042560-199804150-00014.

Abstract

This study was designed to assess HIV risk behaviors, HIV seroprevalence, and tuberculosis (TB) infection in shooting gallery managers in Puerto Rico. The subjects were 464 injection drug users (IDUs), of whom 12.5% reported managing shooting galleries. The median frequency of drug injection was higher in shooting gallery managers than in nonmanagers. A trend was observed for purified protein derivative (PPD) reactivity to increase according to the length of time spent as a gallery manager, but this trend was not statistically significant. However, anergy rates increased significantly with increase in the number of months spent as shooting gallery manager (p = .021). Multivariate analyses showed that IDUs reporting shooting gallery management experience of > or = 25 months were more likely to be infected with HIV. Prevention programs need to emphasize strategies to protect the health of shooting gallery clients and, in particular, shooting gallery managers. Additional studies are required to determine effective strategies for reducing the risk of HIV and TB infection in shooting galleries.

摘要

本研究旨在评估波多黎各射击场管理者的艾滋病毒风险行为、艾滋病毒血清流行率和结核病(TB)感染情况。研究对象为464名注射吸毒者(IDU),其中12.5%报告称管理过射击场。射击场管理者的药物注射频率中位数高于非管理者。观察到纯化蛋白衍生物(PPD)反应性有随担任射击场管理者时间延长而增加的趋势,但该趋势无统计学意义。然而,无反应率随担任射击场管理者月数的增加而显著上升(p = 0.021)。多变量分析显示,报告有≥25个月射击场管理经验的注射吸毒者感染艾滋病毒的可能性更大。预防项目需要强调保护射击场顾客尤其是射击场管理者健康的策略。还需要进一步研究以确定降低射击场艾滋病毒和结核病感染风险的有效策略。

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