Lindsey D P, McKee E L, Hull M L, Howell S M
Biomedical Engineering Graduate Group, University of California, Davis 95616, USA.
IEEE Trans Biomed Eng. 1998 May;45(5):614-9. doi: 10.1109/10.668752.
To reduce space requirements for implant electronics in in vivo telemetry applications, the purpose of this project was to develop and test a new data transmission method that utilizes the ionic properties of bodily fluids as the transmission medium. Motivated by an interest in using the new method to transmit information from a sensor which measures tension in anterior cruciate ligament (ACL) grafts, a sine wave was injected into a cadaver leg using platinum electrodes implanted into the lateral femoral epicondyle. The signal was detected by electromyogram (EMG) surface electrodes. The effect of transmission frequency, the current injected, interelectrode separation, distance of the electrodes from the joint line, and the surface of electrode placement on the signal attenuation was studied. The logarithmic relation between attenuation and frequency was constant from 2 kHz until 10 kHz. For frequencies above 10 kHz, the attenuation increased linearly at the rate of 1 dB/octave. Attenuation was inversely sensitive to both current and interelectrode separation with larger separations and currents giving less attenuation. Attenuation was significantly less for the lateral thigh surface than for the anterior surface and increased with increasing distance from the joint line for both surfaces. For the application of interest here, suitable values of transmission variables to avoid the possible negative consequences of injecting current into living tissue are a current of 3 mA injected at a frequency of 37 kHz. The values of reception variables for minimum attenuation are wide interelectrode separation (5 cm) with the electrodes placed 5 cm proximal of the joint line on the lateral surface of the thigh. With the exception of the surface which is application dependent, these values of the reception variables should also be appropriate for other applications.
为了减少体内遥测应用中植入式电子设备的空间需求,本项目旨在开发并测试一种新的数据传输方法,该方法利用体液的离子特性作为传输介质。出于对使用这种新方法从测量前交叉韧带(ACL)移植物张力的传感器传输信息的兴趣,通过植入股骨外侧髁的铂电极向尸体腿部注入正弦波。信号由肌电图(EMG)表面电极检测。研究了传输频率、注入电流、电极间距、电极与关节线的距离以及电极放置表面对信号衰减的影响。从2 kHz到10 kHz,衰减与频率的对数关系是恒定的。对于高于10 kHz的频率,衰减以1 dB/倍频程的速率线性增加。衰减对电流和电极间距都呈反向敏感,较大的间距和电流导致较小的衰减。大腿外侧表面的衰减明显小于前表面,并且两个表面的衰减都随着与关节线距离的增加而增加。对于此处感兴趣的应用,为避免向活体组织注入电流可能产生的负面后果,合适的传输变量值是在37 kHz频率下注入3 mA的电流。最小衰减的接收变量值是电极间距宽(5 cm),电极放置在大腿外侧表面关节线近端5 cm处。除了取决于应用的表面外,这些接收变量值也应适用于其他应用。