Paukov V S, Saltykov B B, Ermakova N G, Shashlov S V
I.M. Sechenov Moscow Medical Academy.
Arkh Patol. 1998 Jan-Feb;60(1):34-8.
Chronic inflammation (CI) was studied immunologically and immunomorphologically on biopsy and surgical material: interstitial pulmonary diseases, chronic inflammatory processes of the uteri and ovaries, decubitus in the spinal cord damage, trophic ulcers of the limbs, osteomyelitis, chronic abscesses of soft tissues, coccygeal cysts and chronic paraproctitis. The following parameters determine the development of CI: persistence of the damaging agent, immunological insufficiency, mechanisms of autoimmunization, progression of CI according to the principle of vicious circle. CI looses its biological usefulness as a compensatory-adaptive reaction.
我们从活检和手术材料方面，对慢性炎症（CI）进行了免疫学和免疫形态学研究，这些材料包括间质性肺疾病、子宫和卵巢的慢性炎症过程、脊髓损伤后的褥疮、肢体的营养性溃疡、骨髓炎、软组织慢性脓肿、尾骨囊肿和慢性直肠周炎。以下参数决定了慢性炎症的发展：损伤因子的持续存在、免疫功能不全、自身免疫机制、慢性炎症按照恶性循环原则的进展。慢性炎症作为一种代偿性适应反应，失去了其生物学效用。
