Petersson L G, Magnusson K, Andersson H, Deierborg G, Twetman S
Department of Preventive Dentistry, Medical and Dental Health Center, Halmstad, Sweden.
Eur J Oral Sci. 1998 Apr;106(2 Pt 1):623-7. doi: 10.1046/j.0909-8836.1998.eos106203.x.
Development and progression of approximal caries is still difficult to prevent and control even in societies with declining caries prevalence. In this study, a test group of 115 12-yr old children were treated semi-annually with a mixture (1:1) of a varnish containing 0.1% F (Fluor Protector) and 1.0% chlorhexidine (Cervitec). A reference group of 104 children received fluoride varnish treatment (Fluor Protector) semi-annually. Approximal caries was recorded from bitewing radiographs at baseline and after 3 yr. At baseline, total decayed and filled surfaces (DFS) including enamel caries were 1.79+/-2.36 in the reference group and 2.0+/-2.77 in the test group. After 3 yr, the mean approximal caries incidence including enamel caries was 3.01+/-3.74 and 3.78+/-4.32, respectively. The differences at baseline as well as after 3 yr were not statistically significant. The results showed that both groups had a comparatively low incidence of approximal caries during the experimental period, and suggest that a mixture of fluoride and antibacterial varnish had no additional preventive effect on approximal caries incidence compared with fluoride varnish treatments alone.
即使在龋病患病率呈下降趋势的社会中，邻面龋的发生和进展仍然难以预防和控制。在本研究中，对115名12岁儿童的试验组每半年使用含0.1%氟（氟保护漆）和1.0%氯己定（施韦泰克）的混合液（1:1）进行治疗。104名儿童的参照组每半年接受氟化物漆治疗（氟保护漆）。在基线期和3年后通过咬合翼片X线片记录邻面龋情况。基线期，参照组包括釉质龋的龋失补牙面总数（DFS）为1.79±2.36，试验组为2.0±2.77。3年后，包括釉质龋在内的邻面龋平均发病率分别为3.01±3.74和3.78±4.32。基线期和3年后的差异均无统计学意义。结果表明，在实验期间两组的邻面龋发病率均相对较低，这表明与单独使用氟化物漆治疗相比，氟化物和抗菌漆的混合液对邻面龋发病率没有额外的预防作用。
