Petersson L G, Twetman S, Pakhomov G N
Department of Preventive Dentistry, Medical and Dental Center, Halmstad, Sweden.
J Public Health Dent. 1998 Winter;58(1):57-60. doi: 10.1111/j.1752-7325.1998.tb02991.x.
The aim of this two-year community demonstration trial was to study the caries inhibitory effects of semiannual applications of a fluoride varnish in preschool children.
Twenty-four public dental health clinics in the county of Halland, Sweden, with 5,137 preschool children, 4 and 5 years of age, were matched and equally allocated to a fluoride varnish group (n = 2,535) and a reference group (n = 2,602). The children in the fluoride varnish group were treated every six months with topical applications of a silane fluoride varnish, Fluor Protector (0.1% F), while no fluoride varnish was used in the reference group. Both groups received a basic preventive program at annual checkups consisting of dietary counseling and instructions to parents to brush their children's teeth at least once daily with fluoridated dentifrice. Caries data were collected by clinical examinations at baseline and after one and two years.
Caries prevalence at baseline did not differ significantly between the groups. After two years, the mean caries incidence was low and no statistical difference was found in the total number of carious and filled surfaces (dfs) between the two groups. However, the incidence of approximal lesions (dfsa) was significantly lower (P < .05) in the fluoride varnish group than the reference group. Children in the fluoride varnish group with dfs scores of 1-4 and > or = 5 at the start of the study exhibited a statistically significant (P < .05) reduction in approximal caries incidence of 19 percent and 25 percent, respectively, when compared with the reference group.
Preschool children 4 and 5 years of age with clinical caries who receive semiannual applications of a silane fluoride varnish containing 0.1 percent F experience a reduced incidence of approximal caries over two years.
这项为期两年的社区示范试验旨在研究每半年为学龄前儿童应用一次氟化物 varnish 的防龋效果。
瑞典哈兰郡的 24 家公共牙科保健诊所，共有 5137 名 4 至 5 岁的学龄前儿童，将其匹配并平均分为氟化物 varnish 组（n = 2535）和参照组（n = 2602）。氟化物 varnish 组的儿童每六个月接受一次含硅烷氟化物 varnish（氟保护漆，0.1%氟）的局部应用治疗，而参照组不使用氟化物 varnish。两组在年度检查时均接受基本的预防项目，包括饮食咨询以及指导家长每天至少用含氟牙膏为孩子刷牙一次。在基线期以及一年和两年后通过临床检查收集龋病数据。
两组在基线期的龋病患病率无显著差异。两年后，平均龋病发病率较低，两组之间龋坏和充填牙面总数（dfs）未发现统计学差异。然而，氟化物 varnish 组邻面病变（dfsa）的发病率显著低于参照组（P < 0.05）。在研究开始时 dfs 评分为 1 - 4 以及≥5 的氟化物 varnish 组儿童，与参照组相比，邻面龋发病率分别有 19%和 25%的统计学显著降低（P < 0.05）。
4 至 5 岁患有临床龋病的学龄前儿童，每半年应用一次含 0.1%氟的硅烷氟化物 varnish，在两年内邻面龋发病率降低。
