Mayfield L, Nobréus N, Attström R, Linde A
Lund University, Malmö, Sweden.
Clin Oral Implants Res. 1997 Feb;8(1):10-7. doi: 10.1111/j.1600-0501.1997.tb00002.x.
The aim of this study was to evaluate an osteopromotive technique, using a bioabsorbable membrane, for its ability to restitute bone over buccal fenestration and dehiscence defects following fixture installation. 11 patients requiring dental implant treatment and exhibiting sufficient vertical height of the maxilla and compromised bucco-palatal dimensions, as determined clinically and radiographically, were included in the study. 17 Brånemark titanium fixtures were placed with buccal defects which were augmented by a bioabsorbable membrane, Resolut. No complications were observed post-operatively. At 6-8 months, abutment connection was performed, and clinical evaluation of the healed defect area was made. The number of exposed buccal threads at fixture installation (median 8; range 2-19), and abutment connection (median 0; range 0-5), respectively, was compared. Out of the 17 fixtures; 14 exhibited complete coverage with bone, whereas 3 showed some remaining threads. A small punch biopsy taken at abutment connection in an area where the membrane had been placed showed a combination of dense connective tissue and bone. Radiographic evaluation of the marginal periimplant bone level is in progress and results to date show a median bone loss of 1.2 mm after a loading period of 4-6 months. Results show that fixture dehiscence and fenestrations, augmented with this bioabsorbable membrane, demonstrate a highly significant amount of new bone formation.
本研究的目的是评估一种使用可生物吸收膜的骨促进技术，看其在种植体植入后修复颊侧开窗和骨开裂缺损处骨组织的能力。11名需要进行牙种植治疗的患者被纳入研究，这些患者经临床和影像学检查确定上颌垂直高度充足，但颊腭向尺寸不足。植入了17枚Brånemark钛种植体，其颊侧存在骨缺损，使用可生物吸收膜Resolut进行增量处理。术后未观察到并发症。在6至8个月时，进行基台连接，并对愈合的缺损区域进行临床评估。比较了种植体植入时暴露的颊侧螺纹数量（中位数为8；范围为2至19）和基台连接时暴露的颊侧螺纹数量（中位数为0；范围为0至5）。在17枚种植体中，14枚实现了骨组织的完全覆盖，而3枚仍有部分螺纹暴露。在放置膜的区域进行基台连接时取的小块穿刺活检显示为致密结缔组织和骨组织的组合。种植体周围边缘骨水平的影像学评估正在进行中，迄今为止的结果显示，在4至6个月的加载期后，骨吸收的中位数为1.2毫米。结果表明，使用这种可生物吸收膜增量处理种植体开裂和开窗处，可形成大量新骨，差异具有高度统计学意义。
