Giulling E V, Stasenko A A, Polos T M, Perepechenko O I
Lik Sprava. 1997 Nov-Dec(6):63-6.
It has been found out for the first time that in 55% of cases presenting with purulent cholangitis, there are antibodies to a clinical strain of E. coli in the bile taken intraoperatively from major bile duct whereas museum specimens of E. coli strain are free from the above antibodies. Immune complexes were identified in the bile of all examined patients (0.316 +/- 0.085 arbitrary units). In the blood serum of patients with purulent cholangitis, antibodies to the clinical strain E. coli are not detectable, while there are great counts of circulating immune complexes (0.928 +/- 0.242 arbitrary units). Based on the findings obtained a conclusion was reached about relative independence of local immunity of the biliary tract.
首次发现，在55%的化脓性胆管炎病例中，术中从主要胆管获取的胆汁中存在针对大肠杆菌临床菌株的抗体，而大肠杆菌菌株的博物馆标本中则不存在上述抗体。在所有接受检查的患者胆汁中均鉴定出免疫复合物（0.316±0.085任意单位）。在化脓性胆管炎患者的血清中，检测不到针对大肠杆菌临床菌株的抗体，而循环免疫复合物数量很多（0.928±0.242任意单位）。基于所获得的研究结果，得出了关于胆道局部免疫相对独立性的结论。
