肠炎沙门氏菌肠炎亚种都柏林血清型中的四环素抗性
Tetracycline resistance in Salmonella enterica subsp. enterica serovar Dublin.
作者信息
Frech G, Schwarz S
机构信息
Institut für Tierzucht und Tierverhalten der Bundesforschungsanstalt für Landwirtschaft Braunschweig-Völkenrode (FAL), Celle, Germany.
出版信息
Antimicrob Agents Chemother. 1998 May;42(5):1288-9. doi: 10.1128/AAC.42.5.1288.
Abstract
The 47-kbp plasmid pGFT1 from Salmonella enterica subsp. enterica serovar Dublin mediated tetracycline resistance via a tet(A) gene located on an integrated copy of a Tn1721-analogous transposon. The integration site of the transposon was located within the reading frame of a fip gene. Plasmid pGFT1 was shown to be conjugative and to be able to replicate and express tetracycline resistance in Escherichia coli.
摘要
来自肠炎沙门氏菌亚种肠炎血清型都柏林的47千碱基对质粒pGFT1通过位于Tn1721类似转座子整合拷贝上的tet(A)基因介导四环素抗性。转座子的整合位点位于fip基因的阅读框内。质粒pGFT1被证明具有接合性，并且能够在大肠杆菌中复制并表达四环素抗性。
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