Rushdy A A, Stuart J M, Ward L R, Bruce J, Threlfall E J, Punia P, Bailey J R
Public Health Laboratory Service Communicable Disease Surveillance Centre, London.
Epidemiol Infect. 1998 Mar;120(2):125-8. doi: 10.1017/s0950268897008546.
Eight cases of Salmonella senftenberg infection in infants were identified in the first half of 1995 in England, five were indistinguishable S. senftenberg strains. A case-control study showed an association between illness and consumption of one brand of baby cereal (P = 0.03). The cereal manufacturer reported isolating S. senftenberg in June 1994 from an undistributed cereal batch. Outbreak strains and the cereal strain were all plasmid-free in contrast to other human isolates of S. senftenberg in the same period. Changes in the production process were implemented to prevent further contamination. Surveillance centres should strengthen the detection and investigation of outbreaks of gastrointestinal infection in susceptible groups, especially young children. In this outbreak, the study of only five cases led to identification of the vehicle of infection. Even when few cases are reported, epidemiological investigation in conjunction with molecular typing may lead to public health action which prevents continuing or future outbreaks.
1995年上半年，英国确认了8例婴儿感染森夫滕贝格沙门氏菌的病例，其中5例的菌株无法与其他菌株区分。一项病例对照研究表明，患病与食用某一品牌婴儿谷物之间存在关联（P = 0.03）。谷物制造商报告称，1994年6月从未分发的一批谷物中分离出了森夫滕贝格沙门氏菌。与同期其他人类分离出的森夫滕贝格沙门氏菌不同，此次疫情中的菌株和谷物中的菌株都没有质粒。已对生产过程进行了改进，以防止进一步污染。监测中心应加强对易感人群，尤其是幼儿胃肠道感染疫情的检测和调查。在此次疫情中，仅对5例病例进行研究就确定了感染源。即使报告的病例很少，结合分子分型的流行病学调查也可能促成公共卫生行动，从而预防持续或未来的疫情爆发。
