Kirby P J, Morley J, Ponsford J R, McDonald W I
Prostaglandins. 1976 Apr;11(4):621-30. doi: 10.1016/0090-6980(76)90065-4.
Leucocyte migration inhibition in vitro, in response to antigen or mitogen, is suppressed by PGE2 (0.01-1.0 mug/ml). The susceptibility of leucocytes to such inhibition by PGE2 has been compared using cell preparations obtained from normal individuals, multiple sclerosis patients and from patients with other neurological diseases. The results indicate defective reactivity of leucocytes from multiple sclerosis patients.
前列腺素E2（PGE2，0.01 - 1.0微克/毫升）可抑制体外白细胞对抗原或丝裂原的迁移反应。利用从正常个体、多发性硬化症患者以及其他神经系统疾病患者获取的细胞制剂，比较了白细胞对PGE2这种抑制作用的敏感性。结果表明，多发性硬化症患者的白细胞反应性存在缺陷。
