Goodwin J S, Messner R P
Prostaglandins. 1978 Feb;15(2):281-6. doi: 10.1016/0090-6980(78)90167-3.
Kirbey et al have reported that leukocyte function from patients with multiple sclerosis is not suppressed by PGE2, as are normal leukocytes. We examined the ability of PGE2 (0.01-0.5 microgram/ml) to suppress Phytohemagglutinin induced 3H-thymidine incorporation in peripheral blood lymphocytes from multiple sclerosis patients and normals. There was no difference in sensitivity between the two groups. There was also no difference in activity of the prostaglandin producing suppressor cell between the multiple sclerosis patients and controls.
柯尔比等人报告称，与正常白细胞不同，多发性硬化症患者的白细胞功能不会被前列腺素E2抑制。我们检测了前列腺素E2（0.01 - 0.5微克/毫升）抑制多发性硬化症患者和正常人外周血淋巴细胞中植物血凝素诱导的3H - 胸腺嘧啶核苷掺入的能力。两组之间的敏感性没有差异。多发性硬化症患者和对照组之间的前列腺素产生抑制细胞的活性也没有差异。
