Ahmed M, Chilton C P, Munson K W, Williams J H, Pallan J H, Turner G
Department of Urology, Derby City General Hospital, Derby, UK.
Br J Urol. 1998 Apr;81(4):604-6.
To determine the role of colour Doppler imaging (CDI) in the investigation of erectile dysfunction in patients with Peyronie's disease.
Fifty consecutive patients (age 35-75 years) with Peyronie's disease who were considered suitable for surgical treatment were investigated using CDI to determine the haemodynamic variables of penile vasculature after an intracorporeal injection of 20 microg of alprostadil (with manual self-stimulation). A clinician independently recorded the quality of erection and the deformity.
Twenty of 50 patients (40%) considered they had normal erectile function despite their penile deformity and all had normal responses, although they tended to exaggerate the degree of penile deformity. Of the 30 remaining patients, 21 who considered themselves to have erectile dysfunction had normal clinical and CDI haemodynamic responses to alprostadil. The remaining nine patients had a variety of erectile problems and whilst CDI showed altered haemodynamic values, in no case did CDI alter the proposed treatment based on the clinically apparent features of those patients.
Colour Doppler imaging of the penis after pharmacologically induced erection gives anatomical and functional information in patients with Peyronie's disease but does not provide useful additional information to aid the selection of surgical treatment for the disease.
确定彩色多普勒成像（CDI）在佩罗尼氏病患者勃起功能障碍检查中的作用。
连续纳入50例（年龄35 - 75岁）被认为适合手术治疗的佩罗尼氏病患者，在海绵体内注射20微克前列地尔（同时进行手动自我刺激）后，使用CDI来确定阴茎血管系统的血流动力学变量。一名临床医生独立记录勃起质量和畸形情况。
50例患者中有20例（40%）认为尽管阴茎有畸形，但他们的勃起功能正常，且所有患者反应均正常，不过他们往往夸大了阴茎畸形的程度。其余30例患者中，21例自认为有勃起功能障碍的患者对前列地尔有正常的临床和CDI血流动力学反应。其余9例患者有各种勃起问题，虽然CDI显示血流动力学值有改变，但在任何情况下，CDI都没有改变基于这些患者临床明显特征所建议的治疗方案。
药物诱导勃起后阴茎彩色多普勒成像可为佩罗尼氏病患者提供解剖和功能信息，但对该疾病手术治疗的选择并无额外有用信息帮助。
