Saxena R K, Agarwal K, Sahay K B, Guha S K, Dave P K
Centre for Biomedical Engineering, All India Institute of Medical Sciences, New Delhi.
Indian J Med Res. 1998 Mar;107:123-7.
Interplay of the constituents of the articular cartilage synovial fluid combine and its role was examined through the biochemical and rheological studies on bovine joints. The results showed an inverse relationship between the changes in the hyaluronic acid of synovial fluid and the proteoglycans content in articular cartilage together with alterations in the rheological properties of synovial fluid. The study indicated that the inter-movement of fluid solutes across the cartilage and synovial fluid may have an important role in the pathophysiology of osteoarthritis.
通过对牛关节进行生物化学和流变学研究，考察了关节软骨滑液成分的相互作用及其作用。结果表明，滑液中透明质酸的变化与关节软骨中蛋白聚糖含量的变化呈负相关，同时滑液的流变学性质也发生了改变。该研究表明，流体溶质在软骨和滑液之间的相互移动可能在骨关节炎的病理生理学中起重要作用。
