• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

退行性关节病中的软骨蛋白聚糖

Cartilage proteoglycans in degenerative joint disease.

作者信息

Heinegård D, Inerot S, Olsson S E, Saxne T

出版信息

J Rheumatol. 1987 May;14 Spec No:110-2.

PMID:3625664
Abstract

Cartilage content of proteoglycans decreases early in induced degenerative hip joint disease. Remaining molecules show structural changes indicating fragmentation. Fragments lost from the articular cartilage are released to the synovial fluid, where they can be quantified by enzyme linked immunosorbent assay. Their amounts are related to the activity of the disease process.

摘要

在诱导性退行性髋关节疾病早期,蛋白聚糖的软骨含量会减少。剩余分子显示出表明碎片化的结构变化。从关节软骨中丢失的碎片会释放到滑液中,在那里可以通过酶联免疫吸附测定法进行定量。它们的数量与疾病进程的活动有关。

相似文献

1
Cartilage proteoglycans in degenerative joint disease.退行性关节病中的软骨蛋白聚糖
J Rheumatol. 1987 May;14 Spec No:110-2.
2
The release of aggrecan fragments into synovial fluid after joint injury and in osteoarthritis.关节损伤后以及骨关节炎中,聚集蛋白聚糖片段释放至滑液中。
J Rheumatol Suppl. 1995 Feb;43:75-7.
3
Differential levels of synovial fluid aggrecan aggregate components in experimental osteoarthritis and joint disuse.实验性骨关节炎和关节废用中滑液聚集蛋白聚糖聚集体成分的差异水平
J Orthop Res. 1994 Jul;12(4):464-73. doi: 10.1002/jor.1100120403.
4
Changes in joint cartilage aggrecan after knee injury and in osteoarthritis.膝关节损伤及骨关节炎后关节软骨聚集蛋白聚糖的变化
Arthritis Rheum. 1999 Mar;42(3):534-44. doi: 10.1002/1529-0131(199904)42:3<534::AID-ANR19>3.0.CO;2-J.
5
Proteoglycan alterations during developing experimental osteoarthritis in a novel hip joint model.
J Orthop Res. 1991 Sep;9(5):658-73. doi: 10.1002/jor.1100090506.
6
Fibronectin as a marker for osteoarthritis.
J Rheumatol. 1987 May;14 Spec No:28-9.
7
Topographic variation in biglycan and decorin synthesis by articular cartilage in the early stages of osteoarthritis: an experimental study in sheep.骨关节炎早期关节软骨中双糖链蛋白聚糖和核心蛋白聚糖合成的地形学变化:一项在绵羊身上的实验研究
J Orthop Res. 1996 May;14(3):433-44. doi: 10.1002/jor.1100140314.
8
Increased degradation and altered tissue distribution of cartilage oligomeric matrix protein in human rheumatoid and osteoarthritic cartilage.人类风湿性和骨关节炎性软骨中软骨寡聚基质蛋白的降解增加及组织分布改变。
J Orthop Res. 1996 Nov;14(6):946-55. doi: 10.1002/jor.1100140615.
9
Inhibition of COX-2 by celecoxib in the canine groove model of osteoarthritis.塞来昔布对犬骨关节炎沟模型中COX-2的抑制作用。
Rheumatology (Oxford). 2006 Apr;45(4):405-13. doi: 10.1093/rheumatology/kei187. Epub 2005 Nov 15.
10
Target tissue models: cartilage changes in experimental osteoarthritis in the dog.靶组织模型:犬实验性骨关节炎中的软骨变化
J Rheumatol Suppl. 1983 Dec;11:111-3.

引用本文的文献

1
Cationic agent contrast-enhanced computed tomography imaging of cartilage correlates with the compressive modulus and coefficient of friction.阳离子对比剂增强 CT 成像软骨与压缩模量和摩擦系数相关。
Osteoarthritis Cartilage. 2013 Jan;21(1):60-8. doi: 10.1016/j.joca.2012.09.007. Epub 2012 Oct 4.
2
A stable isotope method for the simultaneous measurement of matrix synthesis and cell proliferation in articular cartilage in vivo.一种用于在体内同时测量关节软骨基质合成和细胞增殖的稳定同位素方法。
Osteoarthritis Cartilage. 2009 Jul;17(7):923-32. doi: 10.1016/j.joca.2009.01.006. Epub 2009 Feb 7.
3
Articular cartilage and osteoarthrosis. The role of molecular markers to monitor breakdown, repair and disease.
关节软骨与骨关节炎。分子标志物在监测软骨破坏、修复及疾病中的作用。
J Anat. 1994 Jun;184 ( Pt 3)(Pt 3):477-92.