Beslagić E, Cengić D, Beslagić R, Hamzić S
Katedra za mikrobiologiju, Medicinski fakultet Sarajevo.
Med Arh. 1996;50(3-4):89-91.
After four years of Sarajevo siege, the deblocade started on July 1995. Many soldiers involved in the deblocade developed a clinical symptoms of hemorrhagic fever indicating a possible epidemic.
Suspected patients were treated in the war hospital Igman-Fojnica. Blood samples of all the patients were processed on IgM and IgG antibodies with ELISA test, using "the double sandwich" technique.
IgM and IgG were performed on Puumala (PVV), Hantaan (HTN) and Dobrava antigens. 38 out of 45 treated serums had high antibody titres. Sera of 28 patients had high titres of specific IgM antibodies on Hantaan antigen (12,800). A ten patients had a same titre level for specific antibodies of Puumala antigen. A 20 patients had specific IgG antibodies on Dobrava antigen with the titre 400. Our results confirmed the epidemic for which were responsible two serotypes of HFRS-PVV and HTN. They also proved the existence of a new serotypes appearing for the first time in Sarajevo region. This epidemic confirms that BiH especially Sarajevo region are among the biggest epidemic areas of HFRS in Europa.
在萨拉热窝被围困四年后，1995年7月开始解除封锁。许多参与解除封锁的士兵出现了出血热的临床症状，表明可能发生了疫情。
疑似患者在伊格曼 - 福伊尼察战地医院接受治疗。所有患者的血样采用“双夹心”技术，通过酶联免疫吸附测定法检测IgM和IgG抗体。
对普马拉（PVV）、汉坦（HTN）和多布拉瓦抗原进行了IgM和IgG检测。45份接受检测的血清中有38份抗体滴度较高。28名患者的血清对汉坦抗原具有高滴度的特异性IgM抗体（12,800）。10名患者的普马拉抗原特异性抗体滴度水平相同。20名患者对多布拉瓦抗原具有特异性IgG抗体，滴度为400。我们的结果证实了由两种肾综合征出血热血清型——普马拉型和汉坦型引发的疫情。它们还证明了一种新的血清型首次在萨拉热窝地区出现。此次疫情证实，波黑尤其是萨拉热窝地区是欧洲肾综合征出血热疫情最严重的地区之一。
