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下丘脑乳头体核的电刺激对完整大鼠和辣椒素处理大鼠皮肤血管通透性的影响。

Effect of electrical stimulation of the mamillary nuclei of the hypothalamus on skin vessel permeability in intact and capsaicin-treated rats.

作者信息

Tolochko Z S, Knyazeva G B

机构信息

Laboratory of Functional Neuromorphology, Institute of Physiology, Siberian Division, Russian Academy of Medical Sciences, Novosibirsk, Russia.

出版信息

Neurosci Behav Physiol. 1998 Mar-Apr;28(2):201-5. doi: 10.1007/BF02461968.

DOI:10.1007/BF02461968
PMID:9604224
Abstract

Stimulation of the mamillary nuclei of the rat hypothalamus induced increases in the permeability of forelimb skin microvessels. This effect was not seen in rats stimulated after administration of capsaicin at a dose (150 mg/kg) sufficient to deplete vasoactive neuropeptides from the peripheral nerve terminals of capsaicin-sensitive neurons. These data indicate a role for the mamillary nuclei in central mechanisms modulating the effector functions of primary capsaicin-sensitive neurons.

摘要

刺激大鼠下丘脑乳头体核会导致前肢皮肤微血管通透性增加。在给予足以从辣椒素敏感神经元的外周神经末梢耗尽血管活性神经肽的剂量(150mg/kg)的辣椒素后进行刺激的大鼠中,未观察到这种效应。这些数据表明乳头体核在调节初级辣椒素敏感神经元效应功能的中枢机制中发挥作用。

相似文献

1
Effect of electrical stimulation of the mamillary nuclei of the hypothalamus on skin vessel permeability in intact and capsaicin-treated rats.下丘脑乳头体核的电刺激对完整大鼠和辣椒素处理大鼠皮肤血管通透性的影响。
Neurosci Behav Physiol. 1998 Mar-Apr;28(2):201-5. doi: 10.1007/BF02461968.
2
[The effect of electrostimulation of the hypothalamic mamillary nuclei on the vascular permeability of the skin in intact and capsaicin-pretreated rats].[下丘脑乳头体核电刺激对完整及辣椒素预处理大鼠皮肤血管通透性的影响]
Fiziol Zh Im I M Sechenova. 1996 Dec;82(12):1-5.
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Effect of lesion of the hypothalamic mamillary nuclei on skin blood vessel permeability in normal and capsaicin-pretreated rats.下丘脑乳头体核损伤对正常大鼠和辣椒素预处理大鼠皮肤血管通透性的影响。
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[Changes in the skin microvessel permeability following destruction of the mamillary-tegmental tract in normal and capsaicin-treated rats].[正常和辣椒素处理大鼠乳头体-被盖束破坏后皮肤微血管通透性的变化]
Ross Fiziol Zh Im I M Sechenova. 2001 Jan;87(1):137-41.
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[A change in the permeability of eye microvasculature during damage to the hypothalamic nuclei in intact and rats and rats pretreated with capsaicin].[完整大鼠和用辣椒素预处理的大鼠下丘脑核损伤期间眼微血管通透性的变化]
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[Mammillary complex of the hypothalamus and efferent functions of the capsaicin-sensitive neurons].[下丘脑乳头体复合体与辣椒素敏感神经元的传出功能]
Biull Eksp Biol Med. 1997 Dec;124(12):695-7.
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[Effect of electrical stimulation of the trigeminal nucleus caudatus on the blood microvessel permeability in the eye in normal and capsaicin-treated rats].
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Evidence for the participation of glutamate in reflexes involving afferent, substance P-containing nerve fibres in the rat.谷氨酸参与大鼠中涉及含P物质传入神经纤维的反射的证据。
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Age-related changes of the nucleolar organizer regions without neuron loss in medial mamillary bodies (hypothalamus) in old rats.老年大鼠内侧乳头体(下丘脑)中核仁组织区的年龄相关变化且无神经元丢失。
Mech Ageing Dev. 1999 May 3;108(2):113-25. doi: 10.1016/s0047-6374(98)00157-2.

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Neuroparalytic keratitis and capsaicin.神经麻痹性角膜炎与辣椒素
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Trophic functions of primary sensory neurons: are they really local?初级感觉神经元的营养功能:它们真的是局部性的吗?
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Peptidergic sensory neurons in the control of vascular functions: mechanisms and significance in the cutaneous and splanchnic vascular beds.肽能感觉神经元对血管功能的调控:皮肤和内脏血管床中的机制及意义
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