Sigal L H
Department of Medicine, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, USA.
Rheum Dis Clin North Am. 1998 May;24(2):323-51. doi: 10.1016/s0889-857x(05)70012-0.
Lyme disease is a treatable and curable infectious disease that can be diagnosed with relative confidence with attention to the details of the syndrome and proper use of serologic testing to confirm the clinical diagnosis. Lyme disease should not be a "diagnosis of exclusion," made on the basis of isolated serologic reactivity or because of the presence of symptoms compatible with Lyme disease. The pathogenesis of chronic complaints following infection with B. burgdorferi is often unclear, but such persistent complaints should not automatically be ascribed to ongoing infection. There is no proven role for long-term antibiotics or combination regimens.
莱姆病是一种可治疗且可治愈的传染病，通过关注综合征细节并正确使用血清学检测来确诊临床诊断，就能相对可靠地进行诊断。莱姆病不应基于孤立的血清学反应或因存在与莱姆病相符的症状而成为“排除性诊断”。感染伯氏疏螺旋体后慢性症状的发病机制往往不明，但此类持续症状不应自动归因于持续感染。长期使用抗生素或联合治疗方案并无已证实的作用。
