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危重症患者的急诊内镜逆行胰胆管造影术

Emergency endoscopic retrograde cholangiopancreatography in critically ill patients.

作者信息

Ramirez F C, McIntosh A S, Dennert B, Harlan J R

机构信息

Department of Medicine, Carl T. Hayden Veterans Affairs Medical Center, Phoenix, Arizona 85012, USA.

出版信息

Gastrointest Endosc. 1998 May;47(5):368-71. doi: 10.1016/s0016-5107(98)70220-2.

Abstract

BACKGROUND

The aim of this study was to assess the frequency, indications, yield, and outcome of emergency endoscopic retrograde cholangiopancreatography (ERCP) in critically ill patients.

METHODS

Records of all intensive care unit patients undergoing emergency ERCP were reviewed over a 40-month period. Indications, findings, therapeutic interventions, and survival were analyzed. Those requiring mechanical ventilation at the time of ERCP were in group A and those who did not were in group B.

RESULTS

Of 1781 ERCPs, 32 (1.80%) were performed on intensive care unit patients. Fifteen patients belonged to group A (46.87%) and 17 (53.13%) to group B. The common bile duct was the duct of interest in 30 patients (94%) and was cannulated in 97%. Indications included possible biliary sepsis (68.75%), gallstone pancreatitis, and jaundice (12.5% each). The most common finding was choledocholithiasis (34%), followed by failure to fill the cystic duct (16%) and common bile duct stricture (9%). A normal examination was present in 18.75% of cases. Endoscopic therapy was required in 66.6% of patients in group A and 70.5% of group B. The overall 30-day mortality was 25% (33% for group A and 17.6% for group B) and not related to the ERCP.

CONCLUSIONS

Two percent of all ERCPs performed were on intensive care unit patients (47% requiring mechanical ventilation) primarily to evaluate for possible biliary sepsis. Technical success was not compromised by mechanical ventilation. Therapeutic intervention was required in more than two thirds of patients and the overall 30-day mortality was 25%.

摘要

背景

本研究旨在评估危重症患者紧急内镜逆行胰胆管造影术(ERCP)的频率、适应证、成功率及预后。

方法

回顾40个月期间所有在重症监护病房接受紧急ERCP的患者记录。分析适应证、检查结果、治疗干预措施及生存率。在ERCP时需要机械通气的患者为A组,不需要的为B组。

结果

在1781例ERCP中,32例(1.80%)在重症监护病房患者中进行。15例患者属于A组(46.87%),17例(53.13%)属于B组。30例患者(94%)的目标胆管为胆总管,其中97%成功插管。适应证包括可能的胆源性败血症(68.75%)、胆石性胰腺炎和黄疸(各12.5%)。最常见的检查结果是胆总管结石(34%),其次是胆囊管未显影(16%)和胆总管狭窄(9%)。18.75%的病例检查结果正常。A组66.6%的患者和B组70.5%的患者需要内镜治疗。总体30天死亡率为25%(A组为33%,B组为17.6%),且与ERCP无关。

结论

所有ERCP中有2%是在重症监护病房患者中进行的(47%需要机械通气),主要是为了评估可能的胆源性败血症。机械通气并未影响技术成功率。超过三分之二的患者需要治疗干预,总体30天死亡率为25%。

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