Conway D L, Langer O
Department of Obstetrics and Gynecology, The University of Texas Health Science Center-San Antonio, 78284-7836, USA.
Am J Obstet Gynecol. 1998 May;178(5):922-5. doi: 10.1016/s0002-9378(98)70524-1.
We sought to test the hypothesis that elective delivery of infants diagnosed with macrosomia by ultrasonographic studies in diabetic women will significantly reduce the rate of shoulder dystocia without significantly increasing cesarean section rate.
In a prospective study diabetic women with ultrasonographic estimated fetal weight > or = 4250 gm underwent elective cesarean section; women with estimated fetal weight > or = 90th percentile but < 4250 gm underwent induction of labor. Maternal and neonatal outcomes were analyzed and compared for the periods before and after initiation of the protocol.
A total of 2604 diabetic patients were included in this study. The rate of shoulder dystocia was significantly lower after instituting the protocol (2.4% vs 1.1%, odds ratio 2.2). The cesarean section rate increased significantly between the two periods (21.7% vs 25.1%, p < 0.04). Ultrasonography correctly identified the presence or absence of macrosomia in 87% of patients. Only 10.6% of diabetic patients at term required intervention under the protocol (6.8% labor induction, 3.8% elective cesarean section). The rate of shoulder dystocia was 7.4% in macrosomic infants delivered vaginally.
An ultrasonographically estimated weight threshold as an indication for elective delivery in diabetic women reduces the rate of shoulder dystocia without a clinically meaningful increase in cesarean section rate. This practice, in conjunction with an intensified management approach to diabetes, improves the outcome of these high-risk women and their infants.
我们试图验证这一假设,即对于经超声检查诊断为巨大儿的糖尿病孕妇,择期分娩能显著降低肩难产发生率,且不会显著增加剖宫产率。
在一项前瞻性研究中,超声估计胎儿体重≥4250克的糖尿病孕妇接受择期剖宫产;估计胎儿体重≥第90百分位数但<4250克的孕妇接受引产。对该方案实施前后的母婴结局进行分析和比较。
本研究共纳入2604例糖尿病患者。实施该方案后肩难产发生率显著降低(2.4%对1.1%,优势比2.2)。两个时期之间剖宫产率显著增加(21.7%对25.1%,p<0.04)。超声检查在87%的患者中正确识别了是否存在巨大儿。根据该方案,足月糖尿病患者中仅10.6%需要干预(6.8%引产,3.8%择期剖宫产)。经阴道分娩的巨大儿肩难产发生率为7.4%。
超声估计体重阈值作为糖尿病孕妇择期分娩的指征可降低肩难产发生率,且剖宫产率无临床意义的增加。这种做法,结合强化的糖尿病管理方法,改善了这些高危妇女及其婴儿的结局。