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[放射性核素研究鼻黏膜纤毛运输在复发性呼吸道感染患者中的诊断价值]

[Diagnostic usefulness of radioisotope study of nasal mucociliary transport in patients with recurrent respiratory infections].

作者信息

Armengot Carceller M, Ruiz Hernández G, Romero de Avila C, Cardá C, Basterra Alegría J

机构信息

Servicio de Otorrinolaringología. Hospital General Universitario de Valencia.

出版信息

Rev Esp Med Nucl. 1998;17(1):21-6.

PMID:9609840
Abstract

Mucociliary transport system is thee most primitive and essential airway defense mechanisms. Primary ciliary dyskinesia syndrome (PCDS), an inherited recessive autosomal disease, produces an absence of mucociliary transport, therefore chronic upper and lower airways infections since birth. The study of nasal mucociliary transport by Seroalbumin-Tc99m method is very useful in the diagnosis of this syndrome. According to our experience, mucociliary stasis in a patient with chronic respiratory airways infections is a typical condition of PCDS. Normal nasal mucociliary transport velocity discards the PCDS.

摘要

黏液纤毛运输系统是最原始且至关重要的气道防御机制。原发性纤毛运动障碍综合征(PCDS)是一种常染色体隐性遗传病,会导致黏液纤毛运输功能缺失,从而自出生起就出现慢性上、下呼吸道感染。采用血清白蛋白 - 锝99m法研究鼻黏液纤毛运输对该综合征的诊断非常有用。根据我们的经验,慢性呼吸道感染患者出现黏液纤毛淤滞是PCDS 的典型症状。鼻黏液纤毛运输速度正常可排除PCDS。

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