Hann D M, Jacobsen P B, Azzarello L M, Martin S C, Curran S L, Fields K K, Greenberg H, Lyman G
Psychosocial Oncology Program, H. Lee Moffit Cancer Center and Research Institute, Tampa, FL, USA.
Qual Life Res. 1998 May;7(4):301-10. doi: 10.1023/a:1024929829627.
Although fatigue is one of the most common and debilitating symptoms experienced by cancer patients, it has received little systematic attention. This situation is due in large part to the lack of adequate instruments to measure fatigue. The primary aim of this study was to validate a newly developed measure of fatigue for use with cancer patients: the Fatigue Symptom Inventory (FSI). This 13 item self-report measure was designed to measure the intensity and duration of fatigue and its impact on quality of life. The psychometric properties of the FSI were assessed in women undergoing treatment for breast cancer, women who had completed treatment for breast cancer and women with no history of cancer. A seven-item interference subscale was found to have good internal consistency, with alpha coefficients above 0.90 in all three groups. The complete FSI was found to have rather weak to moderate test-retest reliability among patients in active treatment and healthy comparison subjects assessed on three separate occasions. Convergent validity was demonstrated using comparisons with existing measures of fatigue. Construct validity was demonstrated using comparisons between and within groups as well as comparisons with measures of anxiety and depression. Overall, the FSI was established as a valid and reliable measure of fatigue in cancer patients and healthy individuals. Suggestions are made for the potential application of the measure in clinical research.
尽管疲劳是癌症患者经历的最常见且使人衰弱的症状之一，但它很少受到系统的关注。这种情况在很大程度上是由于缺乏足够的测量疲劳的工具。本研究的主要目的是验证一种新开发的用于癌症患者的疲劳测量方法：疲劳症状量表（FSI）。这个包含13个条目的自我报告量表旨在测量疲劳的强度和持续时间及其对生活质量的影响。在接受乳腺癌治疗的女性、已完成乳腺癌治疗的女性和无癌症病史的女性中评估了FSI的心理测量特性。发现一个包含7个条目的干扰分量表具有良好的内部一致性，在所有三组中阿尔法系数均高于0.90。在接受积极治疗的患者和健康对照受试者中，在三个不同时间点进行评估时，完整的FSI被发现具有较弱到中等的重测信度。通过与现有的疲劳测量方法进行比较来证明收敛效度。通过组间和组内比较以及与焦虑和抑郁测量方法进行比较来证明结构效度。总体而言，FSI被确立为癌症患者和健康个体中疲劳的有效且可靠的测量方法。针对该测量方法在临床研究中的潜在应用提出了建议。
