Maloy A L, Black R D, Segurola R J
The Department of Emergency Medicine, Hospital of Saint Raphael, New Haven, Connecticut 06511, USA.
J Emerg Med. 1998 May-Jun;16(3):437-8. doi: 10.1016/s0736-4679(98)00011-0.
A 31-year-old woman diagnosed with Lyme disease was treated with amoxicillin. One hour after the first antibiotic dose, the patient became acutely ill. She developed hypertension, fever, and rigors. Shortly afterward, she became hypotensive and required fluid resuscitation. This systemic illness, the Jarisch-Herxheimer reaction, was first noted in association with antibiotic therapy for neurosyphilis. Thus, the institution of antibiotic therapy may be complicated by the Jarisch-Herxheimer reaction.
一名31岁被诊断为莱姆病的女性接受了阿莫西林治疗。在首次使用抗生素一小时后，患者病情急转直下。她出现了高血压、发热和寒战。不久后，她血压降低，需要进行液体复苏。这种全身性疾病，即雅里希-赫克斯海默反应，最初是在与梅毒神经病变的抗生素治疗相关联时被发现的。因此，抗生素治疗的开始可能会因雅里希-赫克斯海默反应而变得复杂。
