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[血管源性早期和明显器质性神经精神障碍患者血清游离氨基酸的比较浓度]

[Comparative concentration of serum free amino acids in patients with incipient and manifest organic neuropsychiatric disorders of vascular origin].

作者信息

Tibilova A U, Vorob'eva A D

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(7):1013-6.

PMID:961282
Abstract

The authors conducted a study of the quantitative content of amino acids in the blood serum of patients with initial and expressed organic neuro-psychic disorders of a vascular genesis and in a group of normals of the same age. In patients with initial organic syndromes the content of cystin-cystein and treonine in the blood serum increased. In patients with expressed organic syndromes the content of cystin-cystein increased, while the content of arginine acid and leicyn-isoleicyn decreased as compared to the control group of elderly people. A comparative study of the two groups of patients with organic psychopathology of a vascular origin demonstrated that in vascular dementia there are more severe changes in the content of amino acids in the blood serum.

摘要

作者对患有血管源性初期和明显器质性神经精神障碍的患者以及同年龄正常人群血清中的氨基酸定量含量进行了研究。在患有初期器质性综合征的患者中,血清中的胱氨酸-半胱氨酸和苏氨酸含量增加。在患有明显器质性综合征的患者中,胱氨酸-半胱氨酸含量增加,而与老年对照组相比,精氨酸和亮氨酸-异亮氨酸含量降低。对两组血管源性器质性精神病理学患者的比较研究表明,血管性痴呆患者血清中氨基酸含量的变化更为严重。

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