Patel U, Pinto R S, Miller D C, Handler M S, Rorke L B, Epstein F J, Kricheff I I
Department of Radiology, New York University Medical Center, NY, USA.
AJNR Am J Neuroradiol. 1998 May;19(5):879-87.
Our purpose was to describe the MR imaging features in a series of spinal intramedullary gangliogliomas and to compare these findings with the MR features of intramedullary astrocytomas and ependymomas.
A retrospective analysis was performed of 76 MR examinations in 27 patients with histologically proved spinal ganglioglioma; these were then compared with imaging findings in a representative sample of histologically proved spinal cord astrocytomas and ependymomas.
Statistically significant observations regarding spinal gangliogliomas included young age of the patients (mean, 12 years), long tumor length, presence of tumoral cyst, presence of bone erosion and scoliosis, absence of edema, presence of mixed signal intensity on T1-weighted images, and presence of patchy enhancement and cord surface enhancement. A trend (not statistically significant) was noted for holocord involvement and lack of magnetic susceptibility.
Spinal ganglioglioma can be strongly suspected if MR images reflect the above criteria; however, the ultimate diagnosis still depends on radical resection and appropriate histopathologic investigation.
我们的目的是描述一系列脊髓内神经节胶质瘤的磁共振成像(MR)特征,并将这些发现与脊髓星形细胞瘤和室管膜瘤的MR特征进行比较。
对27例经组织学证实为脊髓神经节胶质瘤患者的76次MR检查进行回顾性分析;然后将这些结果与经组织学证实的脊髓星形细胞瘤和室管膜瘤的代表性样本的影像学表现进行比较。
关于脊髓神经节胶质瘤的具有统计学意义的观察结果包括患者年龄较小(平均12岁)、肿瘤长度较长、存在肿瘤囊肿、存在骨质侵蚀和脊柱侧弯、无水肿、T1加权图像上存在混合信号强度以及存在斑片状强化和脊髓表面强化。全脊髓受累和缺乏磁敏感性有一个趋势(无统计学意义)。
如果MR图像符合上述标准,则可强烈怀疑脊髓神经节胶质瘤;然而,最终诊断仍取决于根治性切除和适当的组织病理学检查。