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舌癌近距离放射治疗:舌癌厚度是区域控制的预后因素吗?

Tongue cancer treated with brachytherapy: is thickness of tongue cancer a prognostic factor for regional control?

作者信息

Yamazaki H, Inoue T, Teshima T, Tanaka E, Koizumi M, Kagawa K, Imai A, Yoshida K, Shiomi H, Shimizutani K, Furukawa S, Fuchihata H, Nakamura H, Inoue T

机构信息

Department of Radiation Oncology, Osaka University Medical School, Japan.

出版信息

Anticancer Res. 1998 Mar-Apr;18(2B):1261-5.

PMID:9615798
Abstract

BACKGROUND

We aimed to investigate the predisposing factor for lymph node metastasis and examine the influence of thickness for lymph node recurrence in oral tongue cancer.

METHODS

We analysed 254 patients with early oral tongue cancer (T1-2N0) who were treated with brachytherapy from 1967 through 1985.

RESULTS

T category (p = 0.005), and thickness (p = 0.04) were identified as a significant predisposing factors for neck failure. 50%, 40% and 30% were the incidences of lymph node metastasis for patients with thickness of tumor more than 11 mm, 6-10 mm and 5 mm or less. Furthermore, T category (largest diameter of lesion) correlates strongly to thickness of tumor.

CONCLUSIONS

Although it is not an independent factor, thickness is a significant predisposing factor for lymph node metastasis.

摘要

背景

我们旨在研究口腔舌癌淋巴结转移的易感因素,并探讨肿瘤厚度对淋巴结复发的影响。

方法

我们分析了1967年至1985年间接受近距离放射治疗的254例早期口腔舌癌(T1-2N0)患者。

结果

T分类(p = 0.005)和肿瘤厚度(p = 0.04)被确定为颈部治疗失败的重要易感因素。肿瘤厚度超过11mm、6-10mm和5mm及以下的患者,其淋巴结转移发生率分别为50%、40%和30%。此外,T分类(病变最大直径)与肿瘤厚度密切相关。

结论

虽然肿瘤厚度不是一个独立因素,但它是淋巴结转移的重要易感因素。

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Tongue cancer treated with brachytherapy: is thickness of tongue cancer a prognostic factor for regional control?舌癌近距离放射治疗:舌癌厚度是区域控制的预后因素吗?
Anticancer Res. 1998 Mar-Apr;18(2B):1261-5.
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Comparison of the long-term results of brachytherapy for T1-2N0 oral tongue cancer treated with Ir-192 and Ra-226.Ir-192和Ra-226治疗T1-2N0期口腔舌癌近距离放射治疗的长期结果比较
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Hautarzt. 2014 May;65(5):390-2. doi: 10.1007/s00105-014-2790-7.
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Relationship between histologic thickness of tongue carcinoma and thickness estimated from preoperative MRI.舌癌组织学厚度与术前MRI估计厚度之间的关系。
Eur Radiol. 2006 Oct;16(10):2242-8. doi: 10.1007/s00330-006-0263-9. Epub 2006 Apr 25.