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古德帕斯彻综合征中免疫球蛋白非线性沉积物的出现。

The appearance of nonlinear deposits of immunoglobulins in Goodpasture's syndrome.

作者信息

Agodoa L C, Striker G E, George C R, Glassock R, Quadracci L J

出版信息

Am J Med. 1976 Sep;61(3):407-13. doi: 10.1016/0002-9343(76)90379-x.

DOI:10.1016/0002-9343(76)90379-x
PMID:961704
Abstract

A twenty year old woman presented with pulmonary hemorrhage and glomerulonephritis with linear deposition of IgG on the glomerular capillary basement membrane, and high titer of antiglomerular basement membrane antibody in her serum. Without treatment, renal function, which was transiently impaired, has improved, pulmonary hemorrhage subsided, and repeat renal biopsies have revealed the appearance of nonlinear in addition to the linear deposition of IgG on the glomerular capillary basement membrane in the face of diminished serum antiglomerular basement membrane antibody titer.

摘要

一名20岁女性出现肺出血和肾小球肾炎,免疫球蛋白G(IgG)在肾小球毛细血管基底膜呈线性沉积,其血清中抗肾小球基底膜抗体滴度较高。未经治疗,曾短暂受损的肾功能已改善,肺出血消退,重复肾活检显示,尽管血清抗肾小球基底膜抗体滴度降低,但IgG在肾小球毛细血管基底膜上除线性沉积外还出现了非线性沉积。

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The appearance of nonlinear deposits of immunoglobulins in Goodpasture's syndrome.古德帕斯彻综合征中免疫球蛋白非线性沉积物的出现。
Am J Med. 1976 Sep;61(3):407-13. doi: 10.1016/0002-9343(76)90379-x.
2
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Goodpasture's syndrome--local and diffuse deposition of antibody in glomerular basement membrane. Case report.肺出血肾炎综合征——抗体在肾小球基底膜的局部及弥漫性沉积。病例报告。
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Recurrent Goodpasture's syndrome.
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Concurrent antiglomerular basement membrane antibody and immune complex mediated glomerulonephritis.合并抗肾小球基底膜抗体和免疫复合物介导的肾小球肾炎。
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The evolution of crescentic nephritis and alveolar haemorrhage following induction of autoimmunity to glomerular basement membrane in an experimental model of Goodpasture's disease.在古德帕斯彻氏病实验模型中,诱导针对肾小球基底膜的自身免疫后新月体性肾炎和肺泡出血的演变。
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Goodpasture's syndrome with asymptomatic renal involvement. Disappearance of antiglomerular basement membrane antibodies deposits after treatment.伴有无症状性肾脏受累的Goodpasture综合征。治疗后抗肾小球基底膜抗体沉积物消失。
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Goodpasture's syndrome in a patient with the Nail-Patella syndrome.一名患有指甲-髌骨综合征的患者出现了肺出血肾炎综合征。
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Goodpasture's disease in the absence of circulating anti-glomerular basement membrane antibodies as detected by standard techniques.经标准技术检测,无循环抗肾小球基底膜抗体情况下的肺出血肾炎综合征。
Am J Kidney Dis. 2002 Jun;39(6):1162-7. doi: 10.1053/ajkd.2002.33385.

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Clinical and pathological features of anti-glomerular basement membrane disease associated with membranous nephropathy: an observational study.抗肾小球基底膜病合并膜性肾病的临床和病理特征:一项观察性研究。
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A case of antiglomerular basement membrane glomerulonephritis complicated by membranous nephropathy.1例抗肾小球基底膜肾小球肾炎合并膜性肾病。
CEN Case Rep. 2014 May;3(1):94-99. doi: 10.1007/s13730-013-0094-x. Epub 2013 Oct 5.
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J Med Case Rep. 2010 Aug 2;4:237. doi: 10.1186/1752-1947-4-237.
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Evolution of antiglomerular basement membrane glomerulonephritis into membranous glomerulonephritis.抗肾小球基底膜肾小球肾炎向膜性肾小球肾炎的演变。
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Anti-glomerular basement membrane antibody-mediated glomerulonephritis due to glue sniffing.
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