Ledger W J, Gee C L, Pollin P A, Lewis W P, Sutter V L, Finegold S M
Am J Obstet Gynecol. 1976 Sep 1;126(1):1-6. doi: 10.1016/0002-9378(76)90455-5.
Oral metronidazole was given as therapy in 25 women with the clinical diagnosis of a postpartum anaerobic soft tissue pelvic infection following a vaginal delivery. There was a good clinical response in 80 per cent of these women. No anaerobic organisms resistant to metronidazole were recovered in the treatment failures. Different specimen collection techniques were evaluated, with anaerobes recovered in 4 per cent of the blood cultures, 26.3 per cent of the transabdominal endometrial aspirations, and 88 per cent of the transcervical endometrial samples. The aerobic recovery of organisms was 4 per cent from blood cultures, 15.8 per cent from transabdominal endometrial aspirations, and 96 per cent from the transcervical approach. The significance of these findings is discussed.
对25例经阴道分娩后临床诊断为产后厌氧性盆腔软组织感染的女性给予口服甲硝唑治疗。这些女性中有80%临床反应良好。在治疗失败的病例中未分离出对甲硝唑耐药的厌氧微生物。对不同的标本采集技术进行了评估，血培养中4%分离出厌氧菌，经腹子宫内膜抽吸物中26.3%分离出厌氧菌，经宫颈子宫内膜样本中88%分离出厌氧菌。血培养中需氧菌的分离率为4%，经腹子宫内膜抽吸物中为15.8%，经宫颈途径中为96%。讨论了这些发现的意义。
