Orban G A, Vogels R
Katholieke Universiteit te Leuven, Laboratorium voor Neuro- en Psychofysiologie, Belgium.
Prog Neurobiol. 1998 Jun;55(2):117-47. doi: 10.1016/s0301-0082(98)00010-0.
Following our strategy of using simple discrimination tasks to investigate the primate visual system, we trained both human and monkey subjects for two orientation discrimination tasks: an identification and a successive discrimination. Contrasting these two tasks allowed us to isolate the temporal comparison component and to relate this component to activity in right fusiform gyrus using Positron Emission Tomography (PET) and to infero-temporal cortex using a lesion approach in monkeys. Single-cell recordings in infero-temporal cortex demonstrated that neurons in this region can contribute to the three processes underlying temporal comparison: (1) sensorial representation of visual stimuli, (2) maintaining a trace of the preceding stimulus, and (3) comparison of the incoming stimulus with that trace. By the same token, a comparison of these two tasks, which use the same input and the same attribute, demonstrates the task dependency of processing in the human and non-human primate visual system.
按照我们使用简单辨别任务来研究灵长类视觉系统的策略，我们对人类和猴子受试者进行了两种方向辨别任务的训练：一种是识别任务，另一种是连续辨别任务。对比这两种任务使我们能够分离出时间比较成分，并利用正电子发射断层扫描（PET）将该成分与右侧梭状回的活动联系起来，同时利用猴子的损伤方法将其与颞下皮质的活动联系起来。颞下皮质的单细胞记录表明，该区域的神经元可以对时间比较所基于的三个过程做出贡献：（1）视觉刺激的感觉表征，（2）保持对先前刺激的痕迹，以及（3）将传入刺激与该痕迹进行比较。同样，这两种使用相同输入和相同属性的任务的比较，证明了人类和非人类灵长类视觉系统中处理过程的任务依赖性。
