仙客来中的五环三萜皂苷

Pentacyclic triterpenoid saponin from Cyclamen coum.

作者信息

Yayli N, Baltaci C, Zengin A, Küçükislamoğlu M, Genç H, Küçük M

出版信息

Planta Med. 1998 May;64(4):382-4. doi: 10.1055/s-2006-957459.

DOI:10.1055/s-2006-957459

PMID:9619124

Abstract

A new triterpenoid saponin, coumoside B, has been isolated from the whole plant of Cyclamen coum. The structure of the compound 3 (C58H92O27) has been deduced by NMR (400 MHz) methods based on the 1H, 13C, DEPT, 1H-1H COSY, HETCOR, NOESY-NMR experiments, and FAB-mass spectrum. Compound 3 was shown to have the structure 16 alpha-hydroxy-3 beta-[[[[beta-xylopyranosyl-(1-->2)]-[beta-glucopyranosyl-(1-->4)]- [beta-glucopyranosyl-(1-->2)]- alpha-arabinopyranosyl]-oxy]olean-12-eno-30,28-lactone and is named coumoside B.

摘要

从仙客来的全株中分离出一种新的三萜皂苷——香豆苷B。通过核磁共振（400兆赫）方法，基于氢谱、碳谱、无畸变极化转移增强谱、氢-氢化学位移相关谱、异核单量子相关谱、核欧沃豪斯效应谱实验以及快原子轰击质谱，推导得出化合物3（C58H92O27）的结构。化合物3具有16α-羟基-3β-[[[[β-D-吡喃木糖基-（1→2）]-[β-D-吡喃葡萄糖基-（1→4）]-[β-D-吡喃葡萄糖基-（1→2）]-α-L-吡喃阿拉伯糖基]-氧基]齐墩果-12-烯-30,28-内酯的结构，被命名为香豆苷B。