对田代娃儿藤中菲并吲哚里西啶生物碱的进一步研究。
Further investigation of phenanthroindolizidine alkaloids from Tylophora tanakae.
作者信息
Abe F, Hirokawa M, Yamauchi T, Honda K, Hayashi N, Ishii M, Imagawa S, Iwahana M
机构信息
Faculty of Pharmaceutical Sciences, Fukuoka University, Japan.
出版信息
Chem Pharm Bull (Tokyo). 1998 May;46(5):767-9. doi: 10.1248/cpb.46.767.
PMID:9621409
Abstract
In addition to ten alkaloids previously described, we have isolated two alkaloid N-oxides from Tylophora tanakae MAXIM. (Asclepiadaceae). Further, the polar fraction of the leaves and caules of this plant cultivated in a farm afforded two new polar alkaloids. The structures of the four products were determined. The relation between the structure and cytotoxic activity of this group of alkaloids is discussed.
摘要
除了先前描述的十种生物碱外，我们还从天星藤（萝藦科）中分离出两种生物碱氮氧化物。此外，在农场种植的这种植物的叶和茎的极性部分产生了两种新的极性生物碱。确定了这四种产物的结构。讨论了这组生物碱的结构与细胞毒性活性之间的关系。
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