美丽文殊兰鳞茎中的细胞毒性和抗疟生物碱。
Cytotoxic and antimalarial alkaloids from the bulbs of Crinum amabile.
作者信息
Likhitwitayawuid K, Angerhofer C K, Chai H, Pezzuto J M, Cordell G A, Ruangrungsi N
机构信息
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois, Chicago 60612.
出版信息
J Nat Prod. 1993 Aug;56(8):1331-8. doi: 10.1021/np50098a017.
From the bulbs of Crinum amabile (Amaryllidaceae), a new alkaloid (-)-amabiline [1], together with the known alkaloids (-)-lycorine [2], (-)-buphanisine [3], (-)-augustine [4], and (+)-crinamine [5], were isolated. The structural characterization of 1 and the revised 1H- and 13C-nmr assignments of 2 are discussed. Alkaloids 2, 4, and 5 were found to be the principal cytotoxic and antimalarial constituents.
从美丽文殊兰（石蒜科）的鳞茎中，分离出一种新生物碱（-）-阿玛灵[1]，以及已知生物碱（-）-石蒜碱[2]、（-）-布法新碱[3]、（-）-奥古斯汀碱[4]和（+）-文殊兰胺[5]。讨论了1的结构表征以及2的1H-和13C-核磁共振谱峰归属的修订。发现生物碱2、4和5是主要的细胞毒性和抗疟成分。
Zotero 插件