硫醇与8-叠氮腺苷衍生物之间的反应。
The reaction between thiols and 8-azidoadenosine derivatives.
作者信息
Cartwright I L, Hutchinson D W, Armstrong V W
出版信息
Nucleic Acids Res. 1976 Sep;3(9):2331-9. doi: 10.1093/nar/3.9.2331.
Abstract
Thiols react at room temperature in dilute solution with 8-azidoadenosine and its nucleotides to give the corresponding 8-aminoadenosine derivatives. The reaction which takes place in the dark is base-catalysed and is particularly rapid when dithiols, e.g. dithiothreitol are used.
摘要
硫醇在室温下于稀溶液中与8-叠氮腺苷及其核苷酸反应，生成相应的8-氨基腺苷衍生物。该反应在暗处进行，由碱催化，当使用二硫醇（如二硫苏糖醇）时反应尤为迅速。
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