Zempsky W T, Anand K J, Sullivan K M, Fraser D, Cucina K
Department of Pediatrics, Egleston Children's Hospital, Emory University School of Medicine, Atlanta, Georgia, USA.
J Pediatr. 1998 Jun;132(6):1061-3. doi: 10.1016/s0022-3476(98)70413-5.
In a double-blind randomized trial including 42 children aged 7 to 18 years, less pain occurred with intravenous placement after iontophoresis of 2% lidocaine with epinephrine, as reported by patients (p = 0.005), parents (p = 0.001), intravenous personnel (p = 0.009), and investigators (p = 0.0002) compared with placebo therapy. Lidocaine iontophoresis provides rapid and effective topical anesthesia for intravenous access in children.
在一项纳入42名7至18岁儿童的双盲随机试验中，与安慰剂治疗相比，据患者（p = 0.005）、家长（p = 0.001）、静脉穿刺人员（p = 0.009）和研究人员（p = 0.0002）报告，2%利多卡因加肾上腺素离子导入后进行静脉穿刺时疼痛较少。利多卡因离子导入可为儿童静脉穿刺提供快速有效的局部麻醉。
