一种用于儿童撕裂伤修复的新型组织粘合剂。
A new tissue adhesive for laceration repair in children.
作者信息
Bruns T B, Robinson B S, Smith R J, Kile D L, Davis T P, Sullivan K M, Quinn J V
机构信息
Department of Emergency Services, T.C. Thompson Children's Hospital, University of Tennessee College of Medicine-Chattanooga Unit 37403, USA.
出版信息
J Pediatr. 1998 Jun;132(6):1067-70. doi: 10.1016/s0022-3476(98)70415-9.
To determine the effectiveness of a new tissue adhesive, 2-Octylcyanoacrylate (2-OCA), for laceration repair, 83 children presenting to T.C. Thompson Children's Hospital Emergency Department with lacerations meeting eligibility requirements between February and June 1996 were randomized to receive 2-OCA or nonabsorbable sutures/staples. The length of time for repair was recorded. The length of time for laceration repair was decreased (2.9 minutes 2-OCA vs 5.8 minutes suture/staple; p < 0.001), the parents' assessment of the pain felt by their children in the 2-OCA group was less, and the wounds closed with tissue adhesive had slightly lower cosmesis scores. 2-OCA is an acceptable alternative to conventional methods of wound repair with comparable cosmetic outcome.
为确定新型组织粘合剂2-氰基丙烯酸辛酯（2-OCA）用于伤口缝合的有效性，1996年2月至6月间，83名符合条件、因伤口裂伤前往T.C.汤普森儿童医院急诊科就诊的儿童被随机分为两组，分别接受2-OCA或不可吸收缝线/吻合钉治疗。记录修复所需时间。结果显示，使用2-OCA进行伤口修复的时间缩短（2-OCA组为2.9分钟，缝线/吻合钉组为5.8分钟；p < 0.001），2-OCA组家长对孩子疼痛程度的评估更低，且使用组织粘合剂闭合的伤口美容评分略低。2-OCA是传统伤口修复方法的一种可接受替代方案，美容效果相当。
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