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Low immunoglobulin G3 levels in wheezy children.

作者信息

Ones U, Güler N, Somer A, Salman N, Yalçin I

机构信息

Department of Paediatric Infectious Diseases, Clinical Immunology and Allergy, Istanbul Medical Faculty, Istanbul University, Turkey.

出版信息

Acta Paediatr. 1998 Apr;87(4):368-70.

PMID:9628287
Abstract

This study aimed to investigate the prevalence of IgG subclass deficiency in wheezy children aged <3 y. Serum levels of IgA, IgE and IgG subclasses were measured in 310 children with recurrent wheezing and in 100 healthy controls. IgG3 levels were below the normal lower limit in 123 (39.6%) patients. This finding may reflect delayed maturation of the immune system, predisposing young children <3 y of age to wheezing.

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