椎间盘内的I型和II型胶原蛋白。纤维环中径向分布的互换。
Types I and II collagens in intervertebral disc. Interchanging radial distributions in annulus fibrosus.
作者信息
Eyre D R, Muir H
出版信息
Biochem J. 1976 Jul 1;157(1):267-70. doi: 10.1042/bj1570267.
Abstract
Intervertebral disc is a highly specialized cartilaginous tissue, containing two genetic types of collagen (I and II). Analysis of peptides from a CNBr digest of collagen showed that the proportions of I and II varied gradually and inversely across pig annulus fibrosus, with exclusively type I at the extreme outer edge and exclusively type II in the nucleus pulposus.
摘要
椎间盘是一种高度特化的软骨组织，含有两种基因类型的胶原蛋白（I型和II型）。对胶原蛋白的溴化氰消化产物中的肽进行分析表明，I型和II型胶原蛋白的比例在猪纤维环中呈逐渐且相反的变化，在最外侧边缘仅为I型，而在髓核中仅为II型。
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本文引用的文献
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Collagen polymorphism: two molecular species in pig intervertebral disc.
FEBS Lett. 1974 Jun 1;42(2):192-6. doi: 10.1016/0014-5793(74)80783-0.
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Collagen: Its structure and function in normal and pathological connective tissues.胶原蛋白：其在正常及病理结缔组织中的结构与功能
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Characterization of collagen peptides by sodium dodecylsulfate-polyacrylamide electrophoresis.通过十二烷基硫酸钠-聚丙烯酰胺凝胶电泳对胶原蛋白肽进行表征。
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The distribution of different molecular species of collagen in fibrous, elastic and hyaline cartilages of the pig.猪的纤维软骨、弹性软骨和透明软骨中不同胶原分子种类的分布。
Biochem J. 1975 Dec;151(3):595-602. doi: 10.1042/bj1510595.
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