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从注射铜的大鼠肝脏中分离(铜、锌)-硫蛋白。

Isolation of (copper, zinc)-thioneins from the livers of copper-injected rats.

作者信息

Bremner I, Young B W

出版信息

Biochem J. 1976 Aug 1;157(2):517-20. doi: 10.1042/bj1570517.

Abstract

The mixed copper- and zinc-binding proteins, with mol.wt. of approx. 12000, induced in rat liver after injection of copper were isolated and characterized as metallothioneins. Three separate forms were obtained, with 7-11% total metal in the protein, equivalent to 2.6-1.6 cysteine residues/metal atom.

摘要

注射铜后在大鼠肝脏中诱导产生的分子量约为12000的铜锌结合混合蛋白被分离出来,并被鉴定为金属硫蛋白。得到了三种不同的形式,蛋白质中总金属含量为7 - 11%,相当于每金属原子有2.6 - 1.6个半胱氨酸残基。

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