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[儿童乳糜泻诊断的拟议标准]

[Proposed criteria for diagnosis of celiac disease in children].

作者信息

Danielsson L, Stenhammar L, Ascher H, Cavell B, Dannaeus A, Hernell O, Ivarsson A, Lindberg T, Lindquist B

机构信息

Barn-och ungdomsmedicinska mottagningen, Norrtälje sjukhus.

出版信息

Lakartidningen. 1998 May 13;95(20):2342-3.

PMID:9630801
Abstract

At a seminar arranged in September 1997 by the Swedish Paediatric Working Group for Coeliac Disease, a diagnostic protocol proposed by the working group was approved by a majority of the paediatricians present, representing almost all paediatric units in Sweden. Briefly, a small bowel biopsy is called for in all children, both at presentation and as a control during gluten-free dieting. Subsequent gluten challenge and biopsy are mandatory only in cases of atypical presentation or if the diagnosis is questioned at some future date. Serum antigliadin and anti-endomysial antibody tests are complementary tools. Agreement was also reached regarding the institution of a national coeliac disease registry.

摘要

在1997年9月由瑞典小儿乳糜泻工作组组织的一次研讨会上,该工作组提出的一份诊断方案获得了与会大多数儿科医生的认可,这些医生代表了瑞典几乎所有的儿科单位。简而言之,所有儿童在初诊时以及在无麸质饮食期间作为对照都需要进行小肠活检。后续的麸质激发试验和活检仅在非典型表现的病例中或未来对诊断有疑问的情况下才是必需的。血清抗麦醇溶蛋白和抗肌内膜抗体检测是辅助手段。关于建立全国乳糜泻登记处也达成了共识。

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