普萘洛尔对心绞痛患者死亡率的影响。
Effect of propranolol on mortality in patients with angina.
作者信息
Lambert D M
出版信息
Postgrad Med J. 1976;52 Suppl 4(603):57-60.
Two hundred and seventeen patients from general practice suffering from angina pectoris were studied over a three year period; 91 patients had beta-blocker treatment, the other 126 did not. The two groups were comparable for age, sex, blood pressure and length of history of angina. The frequency of infarction and mortality from infarction in the two groups was compared. The annual infarct rate in the 126 patients not treated with beta-blockers is shown to be more than three times the rate in the 91 patients treated by beta-blockers. The annual death rate from myocardial infarction is almost four times greater in the group not treated by beta-blockers compared with the beta-blocked group. It is concluded that this provides further evidence that treatment which includes beta-blockade in patients suffering from ischamic heart disease reduces the risk of myocardial infarction and death.
在三年的时间里，对来自普通诊所的217名患有心绞痛的患者进行了研究；91名患者接受了β受体阻滞剂治疗，另外126名患者未接受治疗。两组在年龄、性别、血压和心绞痛病史时长方面具有可比性。比较了两组梗死的发生率和梗死死亡率。结果显示，126名未接受β受体阻滞剂治疗的患者的年梗死率是91名接受β受体阻滞剂治疗患者的三倍多。未接受β受体阻滞剂治疗的组中心肌梗死的年死亡率几乎是接受β受体阻滞剂治疗组的四倍。得出的结论是，这进一步证明，在缺血性心脏病患者中采用包括β受体阻滞在内的治疗方法可降低心肌梗死和死亡的风险。
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