视神经炎患者的视觉激活模式：一项功能磁共振成像初步研究

Visual activation patterns in patients with optic neuritis: an fMRI pilot study.

作者信息

Rombouts S A, Lazeron R H, Scheltens P, Uitdehaag B M, Sprenger M, Valk J, Barkhof F

机构信息

Department of Clinical Physics and Engineering, University Hospital Vrije Universiteit, Amsterdam, The Netherlands.

出版信息

Neurology. 1998 Jun;50(6):1896-9. doi: 10.1212/wnl.50.6.1896.

DOI:10.1212/wnl.50.6.1896

PMID:9633756

Abstract

We studied the use of functional MRI (fMRI) with visual stimulation in nine patients with unilateral optic neuritis. Eight healthy subjects served as controls. Patients showed reduced activation upon stimulation of the affected eye, on average 33% (range 0 to 156%) of the average monocular activation in the control group. Decreased activation was also seen for the unaffected eye (61% of control values, range 3 to 133%). We conclude that fMRI with visual stimulation is feasible in patients with optic neuritis and deserves future study.

摘要

我们对9名单侧视神经炎患者进行了视觉刺激下的功能磁共振成像（fMRI）研究。8名健康受试者作为对照。患者在刺激患眼时激活减少，平均为对照组单眼平均激活的33%（范围0至156%）。未受影响的眼睛也出现激活减少（为对照值的61%，范围3至133%）。我们得出结论，视觉刺激下的fMRI对视神经炎患者是可行的，值得未来进一步研究。