Kumura T, Yamane T, Ohta K, Nakao T, Hino M, Tatsumi N
Osaka City University Hospital, Department of Clinical Hematology.
Rinsho Ketsueki. 1998 May;39(5):398-401.
A 27-year-old male with acute myelogenous leukemia received an allogeneic bone marrow transplantation (allo-BMT). Pneumocystis carinii pneumonia developed on day 65 after the allo-BMT. The patient was intravenously treated with pentamidine. This resulted in a prompt improvement of his dyspnea and fever, but hyperkalemia occurred during the pentamidine therapy. Treatment with pentamidine was stopped and emergent treatment was started. Nevertheless, the serum potassium level rose to 7.7 mEq/l. Urgent dialysis was performed and the serum potassium level fell to 5.0 mEq/l after treatment. Careful monitoring of the serum potassium level is recommended during intravenous therapy with pentamidine.
一名27岁的急性髓性白血病男性接受了异基因骨髓移植(allo-BMT)。在allo-BMT后第65天发生了卡氏肺孢子虫肺炎。患者接受了喷他脒静脉治疗。这使其呼吸困难和发热迅速改善,但在喷他脒治疗期间出现了高钾血症。停止喷他脒治疗并开始紧急治疗。然而,血清钾水平升至7.7 mEq/l。进行了紧急透析,治疗后血清钾水平降至5.0 mEq/l。建议在喷他脒静脉治疗期间仔细监测血清钾水平。