Hawken R J, Beattie C W, Schook L B
Program in Comparative Genomics, College of Veterinary Medicine, University of Minnesota, St Paul, MN 55108, USA.
Rev Sci Tech. 1998 Apr;17(1):17-25. doi: 10.20506/rst.17.1.1098.
The genetics of resistance to disease is an area of great interest in agriculturally important plant and animal species. Selective breeding for resistance to pathogens in plants, animals and insects has demonstrated that resistance and susceptibility to pathogens are controlled by both genetic and environmental factors. The immune loci causally involved in susceptibility and resistance to disease are currently unknown. However, novel enabling molecular technologies promise to assist in unravelling the genetics of the host response to infectious diseases in new ways, and ultimately to improve seed stock genetics.
对重要农业动植物物种而言，抗病遗传学是一个备受关注的领域。针对植物、动物和昆虫的病原体抗性进行的选择性育种表明，对病原体的抗性和易感性受遗传和环境因素共同控制。目前尚不清楚导致易感性和抗病性的免疫基因座。然而，新型分子技术有望以新的方式助力揭示宿主对传染病反应的遗传学奥秘，并最终改善种畜遗传学。
