Ng P, McCluskey P, McCaughan G, Glanville A, MacDonald P, Keogh A
Department of Ophthalmology, Royal Prince Alfred Hospital, Sydney, Australia.
Br J Ophthalmol. 1998 Apr;82(4):423-8. doi: 10.1136/bjo.82.4.423.
To document the nature and frequency of ocular complications in a large group of patients who underwent heart, lung, or liver transplantation.
A retrospective audit of the medical records of all patients undergoing heart, lung, or combined heart-lung transplantation at St Vincent's Hospital, Sydney, or liver transplantation at Royal Prince Alfred Hospital Sydney, was performed to detect patients with symptomatic ocular complications following transplantation. 19 of 860 patients were identified as having ocular complications.
Ocular complications occurred in 2% of patients with 65% of these being opportunistic infections. Herpes group viral retinitis (77%) and fungal chorioretinitis (22%) were seen. Other complications included choroidal pseudolymphoma, central retinal vein occlusion, herpes zoster ophthalmicus, herpetic keratitis, dacryocystitis, cyclosporin retinopathy, and rifabutin associated uveitis.
Herpes group viral retinitis was the most common ocular opportunistic infection and occurred most frequently during the second year after transplantation. Delayed diagnosis was associated with poor visual outcome.
记录一大群接受心脏、肺或肝移植患者眼部并发症的性质和发生率。
对悉尼圣文森特医院接受心脏、肺或心肺联合移植，或悉尼皇家阿尔弗雷德王子医院接受肝移植的所有患者的病历进行回顾性审查，以发现移植后出现有症状眼部并发症的患者。860名患者中有19名被确定有眼部并发症。
2%的患者出现眼部并发症，其中65%为机会性感染。可见疱疹病毒组视网膜脉络膜炎（77%）和真菌性脉络膜视网膜炎（22%）。其他并发症包括脉络膜假淋巴瘤、视网膜中央静脉阻塞、眼部带状疱疹、疱疹性角膜炎、泪囊炎、环孢素性视网膜病变和利福布汀相关性葡萄膜炎。
疱疹病毒组视网膜脉络膜炎是最常见的眼部机会性感染，最常发生在移植后的第二年。诊断延迟与视力预后不良有关。
