Gant T M, Goldberg M W, Allen T D
Department of Cell Biology and Anatomy, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Curr Opin Cell Biol. 1998 Jun;10(3):409-15. doi: 10.1016/s0955-0674(98)80018-5.
At mitosis, the nucleus of higher eukaryotic cells disassemblies into components which subsequently reform functional nuclear envelopes in the two daughter cells. The molecular mechanisms underlying this remarkable morphological reorganization are the focus of active investigation. Recent electron microscopy techniques have provided intriguing glimpses of intermediate structures in both nuclear envelope and nuclear pore complex reassembly.
在有丝分裂过程中,高等真核细胞的细胞核解体成各个组分,这些组分随后在两个子细胞中重新形成功能性核膜。这种显著的形态重组背后的分子机制是当前积极研究的焦点。最近的电子显微镜技术为核膜和核孔复合体重新组装过程中的中间结构提供了饶有趣味的 glimpses。(注:原文中“glimpses”可能有误,推测应为“ glimpses”,暂按此翻译,准确翻译需结合正确原文)