Wutoh A K, Hidalgo J, Rhee W, Bareta J
Department of Clinical and Administrative Pharmacy Sciences, Howard University College of Pharmacy, Nursing, and Allied Health Sciences, Washington, DC 20059, USA.
J Natl Med Assoc. 1998 Jun;90(6):369-73.
This retrospective study evaluated Maryland acquired immunodeficiency syndrome (AIDS) patients who were > or = 50 years at the time of AIDS diagnosis. All patients diagnosed between January 1987 and June 1996 who were > 50 years were included in the cohort. A total of 610 male (82.7%) and 128 female (17.3%) AIDS patients aged > or = 50 were identified. The most common mode of human immunodeficiency syndrome (HIV) transmission was male-to-male sexual contact (34.7%). Additionally, 146 (19.8%) patients contracted HIV through blood transfusions, 93 (12.1%) were infected through heterosexual contact, 134 (18.6) were infected through i.v. drug abuse, and the remaining 109 (14.8%) had unknown risk factors. Data from this preliminary study demonstrate that an alarming percentage of AIDS patients (approximately 10%) in Maryland are aged > or = 50. Sexual contact, either male-to-male or heterosexual transmission, was the route of transmission for nearly 47% of this patient population. However, few research projects, educational programs, or public health initiatives are specifically targeted to this patient population. The increasing life expectancy of AIDS patients as well as the advent of new drug treatments highlights the need for further research to investigate the diagnosis and treatment of AIDS and HIV infection among older patients.
这项回顾性研究评估了在艾滋病诊断时年龄≥50岁的马里兰州获得性免疫缺陷综合征（AIDS）患者。所有在1987年1月至1996年6月期间被诊断出年龄>50岁的患者都被纳入该队列。共识别出610名男性（82.7%）和128名女性（17.3%）年龄≥50岁的艾滋病患者。人类免疫缺陷病毒（HIV）最常见的传播方式是男男性接触（34.7%）。此外，146名（19.8%）患者通过输血感染HIV，93名（12.1%）通过异性接触感染，134名（18.6%）通过静脉药物滥用感染，其余109名（14.8%）的危险因素不明。这项初步研究的数据表明，马里兰州相当比例（约10%）的艾滋病患者年龄≥50岁。性接触，无论是男男性接触还是异性传播，是近47%的该患者群体的传播途径。然而，很少有研究项目、教育计划或公共卫生举措专门针对这一患者群体。艾滋病患者预期寿命的增加以及新药物治疗的出现凸显了进一步研究以调查老年患者艾滋病和HIV感染的诊断与治疗的必要性。
